HA Ultrogel® - 1 L

HA Ultrogel^® resin is a hydroxyapatite agarose composite resin for the separation of biomolecules from research and to manufacturing scale. Hydroxyapatite chromatography is considered to be a “pseudo-affinity” chromatography, or “mixed-mode” ion exchange. It has proven to be an effective purification mechanism in a variety of processes, providing biomolecule selectivity complementary to more traditional ion exchange or hydrophobic interaction techniques.

Features and Benefits

- Unique selectivity and separation mechanism, complementary to traditional IEX and HIC
- Protein purification in neutral, non-denaturating conditions
- High porosity, easy cleaning

Applications

- Purification of human serum proteins
- Purification of basic proteins, of phosphate-dependent proteins and enzymes, and of DNA-dependent enzymes
- Vaccine purification processes, e.g. Bordetella pertussis toxin
- Separation of plant proteins such as lectins, glycoproteins, glycosidases, phospholipidases, sulfohydrolases, sphingomyelinases, transferases, trehalases and kinases