Sartopore® Platinum HB | Cartridge | 0.2µm | 20"
- HB version: Membrane with high bubble point
- Effective Filtration Area: 2.0 m² | 21.5 ft²
- Pore Size: 0.45 µm prefilter | 0.2 µm final filter
- Membrane Material: Modified polyethersulfone
- Sterilization: In-line steamable | Autoclavable
- Adapter: 2-Flange Bayonet | 226 Double O-ring
- O-ring material: Silicone
- Price (CNY):
- CNY18,670.31
- Item No.:
- 5492507H2----HB
- Piece
- 1
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Sartopore® Platinum
Sartopore® Platinum HB (High Bubble Point) is the latest addition to the Sartopore® Platinum family. It offers the same superior performance as the standard version with an increased Bubble Point for challenging processes. This special type of filter is our recommended solution for fill & finish applications. The tighter membrane pores provide highest safety and reliability in sterile filtration.
- High Bubble Point (≥ 4.1 bar) – increased process safety
- Lowest protein adsorption – maximizing product yield
- Excellent wettability – up to 95% less water needed
- No wetting issues during integrity testing – preferred for single-use assemblies
- High chemical compatibility (pH 1-14)
- Temperature stable
- Highest effective filter area (1 m2/10”) – less filter consumption
- Low Extractables Level
- Reliable Integrity Testing
Application
Typical filtration applications include:
- Therapeutica
- Biological Fluids
- Injection solutions
- Media
- Buffer
- Chemical solutions
- Cleaning agents and disinfectants
Membrane
Sartopore® Platinum uses a heterogeneous double membrane made of hydrophilized polyethersulfone, which is characterized by high performance data, excellent wettability, high chemical compatibility, high temperature stability and low protein absorption.
New surface coating
A new hydrophilization process has been developed to permanently modify the membrane surface. In this process, a thermally extremely stable and hydrophilic polymer is applied directly to the entire surface of the membrane. This technology creates the membrane properties that are responsible for the exceptionally good wettability and low protein binding of Sartopore® Platinum, even after extreme chemical and thermal stress. As a result, multiple evaporation cycles in dry and wet conditions and in both directions are possible without negative consequences in terms of wettability and integrity testing.
Compatibility
Sartopore®Platinum Cartridges have been developed for sterilization using either autoclaving or in-line-steaming.The polyethersulfone membrane used is suitable for the filtration of liquids in the pH range of pH 1-14. Therefore, Sartopore® Platinum filters are suitable for most filtration applications in the pharmaceutical and biotechnology sectors.
Excellent wettability
Sartopore® Platinum filters are very easy to wet with the inset of very small amounts of medium. Less than 1 litre of WFI is required to reliably wet a MidiCaps® height 9 (0.26 m²) and then test it for integrity. Due to the excellent wettability, WFI consumption can be significantly reduced, which significantly reduces filtration costs.
Reliable Integrity Testing
Insufficient wetting is one of the main reasons for failing filter integrity tests. In such a case, the affected filter must be rewetted and tested. In addition to the additional costs for the additional tests, there is the risk of losing an entire production batch in the event of repeated failures. The excellent wetting behavior of Sartopore® Platinum helps to eliminate this risk. The use of Sartopore® Platinum results in unprecedented reliability in integrity testing.
Flexibility
Sartopore® Platinum filters are available in a wide range of filtration areas from 4.5 cm² up to 3.0 m² and with a variety of commonly used connections to ensure easy integration into your process regardless of batch size.
Scale Up:
Due to the identical performance data of the different heights in relation to square meters of filter area, Sartopore® Platinum filters are perfectly scalable from small scales to large production scales.
Quality:
Every single element is tested for integrity to meet the highest quality requirements.
Microbial Retention
Sartopore® Platinum filters are validated as sterile filter cartridges according to HIMA and ASTM F-838-05 guidelines.
Documentation:
Sartopore® Platinum filter filters have been designed, developed and produced in accordance with the ISO 9001 certified quality management system. A validation manual is available in accordance with regulatory requirements.
Accessories Information
-
AdapterBottom: 2-Flange Bayonet w. 226 double o-ring | Top: S-Adapter
Applications
-
ApplicationSingle Use Processing
-
IndustryPharma / Biotech
-
Modality
-
Buffer & Auxiliaries Filtration
- Form & Fill
-
Buffer & Auxiliaries Filtration
-
ScaleProduction | Large Scale
Biological Information
-
Bacterial RetentionQuantitative Retention of 1 × E7 CFU/cm² Brevundimonas Diminuta ATCC® 19146 per ASTM methodology
Compliance Information
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Bacterial Endotoxins< 0.25 EU/mL as determined by the LAL test
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Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
-
ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Dimensions
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Filter Size20"(2.0 m² / 21.5 ft²)
-
Filtration Area2 m²
-
Outer Diameter70 mm
General Specifications
-
Capsule/Cartridge FormatCartridges
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Filter FormatCartridges
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Maximum Allowable Back Pressure2 bar (29 psi) at 20°C; 1 bar (14.5 psi) at 80°C
-
Maximum Diffusion50 mL/min at 2.5 bar | 36 psi
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Minimum Required Bubble Point4.1 bar | 59.5 psi
Materials of Construction
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Filter MaterialPolyethersulfone (PES)
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Housing MaterialPolypropylene (PP)
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Material o-ring | sealSilicone (SI)
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Membrane MaterialPolyethersulfone, Hydrophobic (PES)
Operating Conditions
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Maximum Differential Pressure20 °C: 5 bar, 80 °C: 2 bar
Physicochemical Information
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Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
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Pore Size Final-filter0.2 µm
-
Pore Size Pre-filter0.45 µm
Product Information
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BrandSartopore® Platinum HB
-
Pack Size1
Sterility/Purity
-
Delivery ConditionNon sterile - Autoclavable | Steamable
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Sterilization MethodAutoclavable & In-Line Steam Sterilizable
Usage Protocols
-
Sterilization Procedures
-
In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles
- Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles
-
In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles
The Sartocheck® 5 Filter Tester is an automatic filter integrity tester designed to cover the complete range of integrity testing from small syringe filters up to large multiround housings and tangential flow cassettes.
The Sartocheck® 5 Plus Filter Tester is an automatic filter integrity tester with automated Quality Risk Management (QRM) designed to cover the complete range of integrity testing from small syringe filters up to large multi-round housings and tangential flow cassettes.
All members of the Sartoguard family utilize a highly asymmetric polyether sulfone (PES) membrane double layer for unmatched protection of final filters and bioburden reduction with an LRV of 6 per cm². In addition, combinations with different depth filter materials and gamma sterilizable versions are available.