Sartobind® Q 96-Well Plates
Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.
- Item No.:
- 99IEXQ42GC-----V
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Sartobind® Q
Sartobind® Q membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Quaternary ammonium ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.
Applications virus and VLP capture:
As size exclusion effects are negligible, they are suited for purification of viruses and display one order of magnitude higher dynamic binding capacity compared to resin. Viruses such as adeno- or lentiviruses are captured at high flow rates. The material allows also >100 cycles of re-use without loss of binding capacity.
Benefits capture:
- High speed purification at 5 - 30 bed volumes per minute
- No size exclusion effects for large proteins an viruses / VLPs
- >10fold higher binding capacities compared to conventional resins
Applications flow-through polishing:
Sartobind Q is the perfect tool for the flow-through polishing of valuable proteins such as monoclonal antibodies. The bed volumes can be kept sufficiently small during the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins from such pharmaceutical proteins.
Benefits flow-through polishing:
- Virus clearance > 6 log
- DNA below detection limit
- Host cell protein removal > 99 %
- Endotoxin removal > 5 log
- Save 80 % of column costs
Easy to use:
- Plug and play devices from 0.08 mL to 5 L
- Can be used like a filter
- Flow rate up to 30 bed volumes/min
- Re-usable or disposable
Application Notes
Brochure
Flyer
Applications
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ApplicationScreening
Connections (Physical)
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Connector(s)N/A
Dimensions
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Bed Height0.8 mm
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Dimensions WxDxH128 × 85.5 × 25 mm
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Membrane Area0.7 cm²
Features
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ReusableNo
Materials of Construction
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Housing MaterialPolypropylene (PP)
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Material 8-stripPolypropylene (PP)
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Material Holding FramePolystyrene
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Materials of ConstructionPolyester
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Membrane MaterialStabilized reinforced cellulose
Operating Conditions
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Maximum Operating Pressure35 kPa
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pH StabilitypH 2 – 14 (short term)
Physicochemical Information
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Bed Volume19 µL/well
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LigandQuaternary ammonium
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Ligand Density2 – 5 µeq/cm²
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Pore Size3 – 5 µm
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Reference ProteinBovine serum albumin (BSA)
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Typical Dynamic Binding Capacity 10% per unit0.55 mg/well
Product Information
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BrandSartobind® Q
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Membrane Adsorber Format96-Well Plates
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Membrane TypeStrong anion exchange membrane
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Pack Size2
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TypeMembrane adsorber (96-well plate)
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What you receive
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2 plates
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4 deep well collection plate 2 ml
- 1 operating instruction
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2 plates
Sterility/Purity
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Sterilization MethodAutoclavable