Sartobind® S 96-Well Plates

Tech Support Documents
Sartobind® S 96-Well Plates
 

Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

Pack Size
Item No.: 
99IEXS42GC-----V
Availability: 

*Custom/bulk order quotes are provided within 72 hours of request.

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Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.

Applications:

The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).

Benefits:

The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.

  • High speed host cell protein removal up to 30 bed volumes/ min
  • Aggregate removal

Easy to use:

  • Plug and play devices from 0.08 ml to 5 l
  • Can be used like a filter
  • Flow rate up to 30 bed volumes/min
  • Disposable or re-usable

Applications

  • Application
    Screening

Connections (Physical)

  • Connector(s)
    N/A

Dimensions

  • Bed Height
    0.8 mm
  • Dimensions WxDxH
    128 × 85.5 × 25 mm
  • Membrane Area
    0.7 cm²

Features

  • Reusable
    No

Materials of Construction

  • Housing Material
    Polypropylene (PP)
  • Material 8-strip
    Polypropylene (PP)
  • Material Holding Frame
    Polystyrene
  • Materials of Construction
    Polyester
  • Membrane Material
    Stabilized reinforced cellulose

Operating Conditions

  • Maximum Operating Pressure
    35 kPa
  • pH Stability
    pH 3 – 14 (short term)

Physicochemical Information

  • Bed Volume
    19 µL/well
  • Ligand
    Sulfonic acid
  • Ligand Density
    2 – 5 µeq/cm²
  • Pore Size
    3 – 5 µm
  • Reference Protein
    Lysozyme
  • Typical Dynamic Binding Capacity 10% per unit
    0.48 mg/well

Product Information

  • Brand
    Sartobind® S
  • Membrane Adsorber Format
    96-Well Plates
  • Membrane Type
    Strong cation exchanger
  • Pack Size
    2
  • Type
    Membrane adsorber (96-well plate)
  • What you receive
    • 2 plates
    • 4 deep well collection plate 2 ml
    • 1 operating instruction
  • Vivawell Vac96 Vacuum Manifold
    Vivawell Vac96 Vacuum Manifold
    Item no.
    VW96VAC01

    The Vac96 vacuum manifold has been designed specifically for use with Sartobind® 96 multiwell plates. The long drip nozzles on the outlet eliminate cross-talk between flow channels.