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- CM Ceramic HyperD® F Pre-packed Columns
CM Ceramic HyperD® F PRC Column - 1 mL
CM Ceramic HyperD® is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.
- Pre-packed columns simplify resin screening and selection
- Ideal for process step optimization
- RoboColumn® format is especially suited for high throughput process development (HTPD)
- Item No.:
- PRC05X050CMCHDF
- Availability:
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CM Ceramic HyperD® is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.
- Pre-packed columns simplify resin screening and selection
- Ideal for process step optimization
- RoboColumn® format is especially suited for high throughput process development (HTPD)
Overview
Specifications
Choose your CM Ceramic HyperD® F
CM Ceramic HyperD® F ion exchange chromatography resin is designed using proprietary gel-in-a-shell design that provides rapid mass transfer and effective binding. It relies on a high capacity hydrogel, polymerized within the gigapores of a rigid ceramic bead. This salt-tolerant resin reduces Ultrafiltration (UF) and Diafiltration (DF) requirements, enhancing process efficiency.
CM Ceramic HyperD® pre-packed columns are designed to simplify resin screening and selection, making them ideal for optimizing process steps. The RoboColumn® format is particularly suited for high throughput process development (HTPD), allowing for efficient and streamlined purification processes.
Features and Benefits
- High dynamic binding capacity at high flow rates
- Truly rigid, non-compressible resin
- Salt tolerant CM Ceramic HyperD™ F resin reduces Ultrafiltration/Diafiltration (UF/DF) requirements
Applications
- Recombinant proteins
- Purification of enzymes, plasma proteins
- Vaccines
- Direct capture of monoclonal antibodies
- IgM
Applications
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ApplicationResin screening and process optimization
Compliance Information
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Quality Standards
-
CoA
- RSF (upon request)
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CoA
Dimensions
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Bead Size50 µm
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Bed Height50 mm
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Dimensions5 x 50 mm
General Specifications
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Flow Ratetypically 300 to 600 cm/h (1 to 2 mL/min) with < 1.5 bar (22psi)
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Resin FormatPre-packed column
Materials of Construction
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Base MatrixCeramic Beads
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Materials of ConstructionPolypropylene
Operating Conditions
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Operating Pressure< 3 barg (44psi)
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pH Stability1 to 14 (short term), 2 to 12 (long term)
Physicochemical Information
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Bed Volume1 mL
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LigandCarboxymethyl
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Ligand Density250-400 µeq/mL
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Reference ProteinHuman polyclonal IgG
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Typical Dynamic Binding Capacity 10% per mL> 110 g/L
Product Information
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BrandCM Ceramic HyperD®
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Pack Size1 column per pack
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Pack Volume1 mL
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Resin Delivery Condition20% EtOH/150 mM NaCl
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Resin TypeWeak cation exchanger
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What you receive1 columnInstruction for use
Storage Conditions
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Storage Conditions1M NaCl with 20% EtOH, 1.2 mM EDTA