LipidBrick® Cell Ready 0,3 mL

Democratizing Gene-Modified Cell Therapy, Delivering Excellence: LipidBrick® Cell Ready is a Ready-to-Use Lipid-based Nanoparticle Solution Tailored for the Ex Vivo Transfection of Immune & Stem cells for Gene-Modified Cell Therapy applications.

Amount of Reagent
Item No.: 
101000301
*Custom/bulk order quotes are provided within 72 hours of request.
LipidBrick® Cell Ready 0,3 mL
LipidBrick® Cell Ready 0,3 mL

Democratizing Gene-Modified Cell Therapy, Delivering Excellence: LipidBrick® Cell Ready is a Ready-to-Use Lipid-based Nanoparticle Solution Tailored for the Ex Vivo Transfection of Immune & Stem cells for Gene-Modified Cell Therapy applications.

Item No.:
101000301

Overview

Specifications

LipidBrick® Cell Ready is an advanced non-viral delivery system utilizing pre-formed lipid-based nanoparticles. It is meticulously optimized for the efficient delivery of nucleic acids delivery to a variety of human primary immune and stem cell types, such as T cells, NK cells and CD34+ hematopoietic stem cells. This versatile solution supports both transient protein expression, aiding in the development of mRNA CAR-T/NK cell therapies, and stable cell modifications through the delivery of genetic engineering tools such as CRISPR/transposons. In addition, it is designed to be gentle to cells, preserving cell growth and function, as well as offering scalability from well-plate screenings to bioreactor gene-modified cell therapy production.

Key Benefits:

  • Cost-Efficiency: Ready-to-use reagent, with no specific equipment nor consumables required.
  • High Performance: Excels in transient expression & stable modification using gene editing tools.
  • High Cell Viability: Preserves cell viability, growth and function.
  • Scalability: Suitable for well-plate screenings to bioreactor production.
  • Flexibility: Accommodates diverse nucleic acid payloads across various immune & stem cells

Applications

  • Application
    Ex Vivo Gene-Modified Cell Therapy
  • Cell Type
    • Immune cells (e.g. T, NK, Dendritic, etc.)
    • Stem cells (e.g. CD34+ HSCs)

Biological Information

  • Molecule delivered
    • mRNA, saRNA
    • gRNA
    • pDNA
    • nanoplasmid
    • circRNA
  • Number of transfections
    Depending on the application, 0.3 mL is sufficient to transfect up to: ~1.8-5.6x108 human primary T cells ~1.8-2.8x108 human primary NK cells ~1.8-3.7x108 human CD34+ HSCs

Compliance Information

  • Product Documentation
    • Protocol 
    • Certificate of Analysis 
    • Master Safety Data Sheet

General Specifications

  • Amount of Reagent
    0.3 mL
  • Reagents and Kits Type
    LipidBrick® Cell Ready

Product Information

  • Pack Size
    mRNA buffer 60 mL Bottle
  • Provided With
    mRNA buffer

Storage Conditions

  • Storage Conditions
    • 5 °C ± 3 °C
    • Do not freeze

Volume

  • Volume
    0.3 mL