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LipidBrick® Cell Ready 0,3 mL
Democratizing Gene-Modified Cell Therapy, Delivering Excellence: LipidBrick® Cell Ready is a Ready-to-Use Lipid-based Nanoparticle Solution Tailored for the Ex Vivo Transfection of Immune & Stem cells for Gene-Modified Cell Therapy applications.
- Item No.:
- 101000301
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Democratizing Gene-Modified Cell Therapy, Delivering Excellence: LipidBrick® Cell Ready is a Ready-to-Use Lipid-based Nanoparticle Solution Tailored for the Ex Vivo Transfection of Immune & Stem cells for Gene-Modified Cell Therapy applications.
Overview
Specifications
Choose your Non-Viral Delivery Solutions
LipidBrick® Cell Ready is an advanced non-viral delivery system utilizing pre-formed lipid-based nanoparticles. It is meticulously optimized for the efficient delivery of nucleic acids delivery to a variety of human primary immune and stem cell types, such as T cells, NK cells and CD34+ hematopoietic stem cells. This versatile solution supports both transient protein expression, aiding in the development of mRNA CAR-T/NK cell therapies, and stable cell modifications through the delivery of genetic engineering tools such as CRISPR/transposons. In addition, it is designed to be gentle to cells, preserving cell growth and function, as well as offering scalability from well-plate screenings to bioreactor gene-modified cell therapy production.
Key Benefits:
- Cost-Efficiency: Ready-to-use reagent, with no specific equipment nor consumables required.
- High Performance: Excels in transient expression & stable modification using gene editing tools.
- High Cell Viability: Preserves cell viability, growth and function.
- Scalability: Suitable for well-plate screenings to bioreactor production.
- Flexibility: Accommodates diverse nucleic acid payloads across various immune & stem cells
Applications
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ApplicationEx Vivo Gene-Modified Cell Therapy
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Cell Type
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Immune cells (e.g. T, NK, Dendritic, etc.)
- Stem cells (e.g. CD34+ HSCs)
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Immune cells (e.g. T, NK, Dendritic, etc.)
Biological Information
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Molecule delivered
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mRNA, saRNA
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gRNA
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pDNA
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nanoplasmid
- circRNA
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mRNA, saRNA
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Number of transfectionsDepending on the application, 0.3 mL is sufficient to transfect up to: ~1.8-5.6x108 human primary T cells ~1.8-2.8x108 human primary NK cells ~1.8-3.7x108 human CD34+ HSCs
Compliance Information
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Product Documentation
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Protocol
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Certificate of Analysis
- Master Safety Data Sheet
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Protocol
General Specifications
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Amount of Reagent0.3 mL
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Reagents and Kits TypeLipidBrick® Cell Ready
Product Information
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Pack SizemRNA buffer 60 mL Bottle
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Provided WithmRNA buffer
Storage Conditions
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Storage Conditions
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5 °C ± 3 °C
- Do not freeze
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5 °C ± 3 °C
Volume
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Volume0.3 mL