Virosart® HF offers high-performance virus filtration for monoclonal antibodies and recombinant proteins, ensuring LRV ≥ 4 log₁₀ for small viruses and LRV ≥ 6 log₁₀ for large ones. Available in formats from 1.7 cm² to 14.4 m², its PES membrane provides rapid processing, scalability, and regulatory compliance, ideal for biopharmaceutical applications.

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Virosart® HF
Virosart® HF

Virosart® HF offers high-performance virus filtration for monoclonal antibodies and recombinant proteins, ensuring LRV ≥ 4 log₁₀ for small viruses and LRV ≥ 6 log₁₀ for large ones. Available in formats from 1.7 cm² to 14.4 m², its PES membrane provides rapid processing, scalability, and regulatory compliance, ideal for biopharmaceutical applications.

Item No.:
M_Virosart_HF

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The Virosart® HF product family offers reliable and efficient high-performance virus filtration solutions. Virosart® HF meets the diverse needs of the biopharmaceutical industry, from laboratory research to large-scale manufacturing. Its range of formats and robust design make it a versatile and cost-effective option for ensuring product integrity and purity.

Key Features

  • Advanced Filtration Technology: The modified PES membrane in hollow fiber format offers high flow rates and excellent capacity, ensuring consistency and scalability from lab to process scale.
  • Robust Virus Clearance: The membrane retains small, non-enveloped viruses with LRV ≥ 4 log₁₀ and large, enveloped viruses with LRV ≥ 6 log₁₀, ensuring efficient virus removal, independent of operating and pressure conditions.
  • Cost Efficiency: High packing density results in low hold-up and flushing volumes, reducing footprint requirements.
    Ready to Use: Sterile delivery facilitates ease of use and quick installation.
  • Regulatory Compliance: Manufactured under ISO 9001 certified Quality Management System and non-pyrogenic as per USP Bacterial Endotoxins standards.
  • Versatile Device Formats: Available in lab scale, mid-scale, process scales and Maxicaps® MR.
  • Integrity Testing: Reliable integrity testing using Sartocheck® technology. Furthermore, each unit is integrity tested (except non-IT tested version of lab module, see specifications) and complies with industry standards, ensuring reliability and performance.
  • Operating Parameters:
    - Filtration pressure: Max. 5.0 bar (73 psi) at 20°C
    - Reversed filtration pressure: Max. 2.5 bar (36.3 psi) at 20°C

Ordering Information

  • Hollow fiber modules: Various filtration areas
  • Maxicaps® MR: Various configurations to support large scale volumes
  • Mid-scale and process-scale modules: Additionally available as virus filter transfer units. They are delivered pre-assembled and
    sterile (y-irradiated).

Applications

  • Application
    • mAB Production
    • Recombinant Protein Production

Materials of Construction

  • Filter Material
    Polyethersulfone (PES)

Physicochemical Information

  • Pore Size
    20 nm (nominal)

Product Information

  • Brand
    Virosart® HF