Sartopore® 2 XLG Cartridge 10"
Sartopore® 2 XLG filter cartridge is a high-performance PES membrane filter, used in stainless steel housings, to perform sterilizing-grade filtration in bioprocesses. Its unique membrane composition boosts the filtration efficiency in downstream processing of proteins or lipid nanoparticles.
Pore Size: 0.8 µm | 0.2 µm
- Item No.:
- 5442507G1
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Sartopore® 2
Sartopore® 2 XLG is a high-performance membrane filter, offering more than just reliable sterilizing-grade filtration in biopharmaceutical processes. Its highly asymmetric membrane structure and composition of 0.8µm prefilter in front of the sterilizing-grade filter (0.2 µm pore size), boosts the filtration efficiency in downstream processing of protein-based therapies or innovative drug delivery systems like lipid nanoparticles (LNPs). Thanks to the outstanding total throughput, Sartopore® 2 XLG is also a choice for filtration after the cell harvest.
The XL in its name indicates an increased effective filtration area (EFA). By using a different pleating technology, the EFAs of Sartopore ® 2 XLG filters are - depending on filter format - 30-40% higher than for the conventional Sartopore® 2 filters. This leads to higher total throughput per filter element and less filter consumption or enables the use of a smaller filter element for a process to reduce the footprint and waste.
Sartopore® 2 XLG filters are available in all established formats with different sizes and for different purposes: Conventional filter cartridges for stainless steel housings or single-use capsules like the small Capsules, the mid-sized Midicaps®, the larger Maxicaps® / T-Style Maxicaps® and the Maxicaps® MR for very large volumes (e.g, clarification after bioreactor harvest). The single-use capsules are available as pre-sterilized (by autoclaving), autoclavable or gamma irradiatable versions. The wide range of different filter formats and sizes ensures that customers can easily scale up their process during drug development process – from preclinical to commercial scale.
Focus Applications
- Cell culture media preparation
- Post cell harvest filtration
- Protein-based therapies (Downstream intermediates, form & fill)
- Lipid nanoparticles (Downstream intermediates, form & fill)
Your Benefits
- Increased total throughput leads to less filter consumption, less process interruptions and reduced costs
- Increased effective filtration enables the use of smaller filters to reduce footprint and waste
- Proven and robust membrane chemistry known from the widely established Sartopore® 2 family lowers validation effort in case of process optimization
- Broad range of formats and sizes assures scalability and enables use of Sartopore® 2 XLG along the whole drug product lifecycle: from development to commercial processes
- Offers secure bacterial retention according to ASTM guidelines
Applications
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Application8799048270432
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Industry8799054758496
Biological Information
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Bacterial Retention8798947508832
Compliance Information
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Bacterial Endotoxins8798947377760
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Biological Reactivity8804252484192
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Extractables8798986044000
Connections (Physical)
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Connector Inlet8798969660000
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Connector Outlet8798969660000
Dimensions
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Filter Size8798990860896
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Filtration Area0.8 m²
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Outer Diameter70 mm
General Specifications
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Capsule/Cartridge Format8798961861216
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Maximum Allowable Back Pressure2 bar (29 psi) at 20°C; 1 bar (14.5 psi) at 80°C
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Maximum Diffusion23 mL/min at 2.5 bar | 36 psi at 20 °C per 10 inch element
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Minimum Required Bubble Point3.2 bar | 46 psi
Materials of Construction
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Housing Material8804580328032
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Material o-ring | seal8799065703008
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Membrane Material8799043650144
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Support Fleece8799043191392
Operating Conditions
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Maximum Differential Pressure8799040963168
Physicochemical Information
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Non-Fiber Releasing8799064457824
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Pore Size Final-filter0.2 µm
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Pore Size Pre-filter0.8 µm
Product Information
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Brand8798953472608
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Pack Size1
Sterility/Purity
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Sterilization Method8799086674528
Usage Protocols
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Sterilization Procedures
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In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles
- Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles
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In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles
All members of the Sartoguard family utilize a highly asymmetric polyether sulfone (PES) membrane double layer for unmatched protection of final filters and bioburden reduction with an LRV of 6 per cm². In addition, combinations with different depth filter materials and gamma sterilizable versions are available.