Study factors for manufacturability

Collect important information about the behaviour of the molecules in downstream processing already in an early stage

Automated, parallel trials

Up to 16 channels can be managed by one control station

Lowest process volumes

Small scale screening with 10 cm² membrane area | 5 mL recirculation volume

Flexibility of two different process scales

Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area

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The High Throughput Solution for Parallel Screening

Ambr® Crossflow provides at early development stages access to molecule behavior related to viscosity, buffer composition, shear stress and performance in membrane processes. It enables a lot of important additional decision criteria for the final candidate selection and speeds up this process significantly.

A small scale, high throughput automated system enables greater number of molecule | buffer combinations and process control conditions to be investigated. As a result early stage R&D productivity and efficiency will be improved significantly while costs per experiment are reduced.

Ambr® Crossflow is a benchtop crossflow system optimised for ultrafiltration and diafiltration applications. It is a small scale screening system with a minimum recirculation volume of 5 mL and a dedicated new range of Ambr® CF filter cassettes with 10 cm² membrane area.

Parallel operation is achieved with 4 independent crossflow channels per module, with up to 4 modules managed by one control station. This means Ambr® Crossflow is capable of performing membrane screenings with up to 16 Ambr® CF filters simultaneously.

Intuitive hardware and software design ensures that the system is quick to set up and easy to use, while full system automation ensures reliable process control and reduced manual intervention.

General Specifications

  • Pump Output
    0 – 50 mL/min

Materials of Construction

  • Recirculation Vessel
    Polystyrene (PS)

Operating Conditions

  • Maximum Operating Pressure
    3 bar (43.5 psi)
  • Minimum Operating Volume
    5 mL

Product Information

  • Brand
    Ambr® crossflow

Volume

  • Recirculation Vessel Volume
    120 mL