HyperCel STAR AX is an industry-scalable anion exchange chromatography resin designed for high productivity protein capture at moderate or higher salt conductivity (2 to 15 mS/cm), typical of undiluted biological feedstocks (e.g. mammalian cell culture supernatants, E. coli feedstock, plasma, etc.).
Bulk resins are available in various quantities to support different scaling processes, ensuring flexibility and adaptability. Perfect for large-scale purification processes.
Features and Benefits
- High dynamic binding capacity (DBC) at short residence time (2 minutes or lower)
- Direct capture of protein from undiluted feedstock at moderate or high conductivity
- Excellent flow rate properties for fast feedstock processing
- Distinctive selectivity, consistent in a broad conductivity range (2 – 15 mS/cm)
- Enhanced process economics
- Manufactured at large scale and to meet the demands of commercial users and regulatory authorities
Applications
- Direct capture of recombinant proteins, mono- and poly-clonal antibodies, plasma derivatives
- Direct Capture of Albumin from Undiluted Plasma
- Early Removal of CHOPs before Protein A Capture of a Monoclonal Antibody (MAb)