Methyl Ceramic HyperD® F

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Methyl Ceramic HyperD® F
 

Methyl Ceramic HyperD® F is a soft hydrophobic interaction (HIC) Resin with CEX interactions. It is specifically designed for the efficient and scalable purification of biomolecules. It provides superior dynamic capacity for proteins over a full range of linear velocities.

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Methyl Ceramic HyperD® F
Methyl Ceramic HyperD® F

Methyl Ceramic HyperD® F is a soft hydrophobic interaction (HIC) Resin with CEX interactions. It is specifically designed for the efficient and scalable purification of biomolecules. It provides superior dynamic capacity for proteins over a full range of linear velocities.

Item No.:
M_Methyl_Ceramic_HyperD

Overview

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Methyl Ceramic HyperD® F is designed for efficient and scalable capture of biomolecules. The sorbent has a unique "gel-in-a-shell" design that provides rapid mass transfer and effective binding. It employs a soft, high-capacity hydrophobic (-CH3) functionalized hydrogel which is polymerized within the large pores of a high dimensional rigid ceramic bead.

Features and Benefits

  • Can be used for very hydrophobic target molecules or impurities
  • Does not shrink or swell with changes in pH or conductivity
  • Shows superior dynamic capacity for proteins over a full range of linear velocities
  • High dynamic binding capacity at high flow rates
  • Truly rigid, non-compressible resin

Applications

  • Efficient and scalable capture of biomolecules

Applications

  • Application
    Preparative protein purification

Compliance Information

  • Quality Standards

    CoA
    RSF upon request

Dimensions

  • Bead Size
    50 µm

General Specifications

  • Flow Rate
    >300cm/h with <3 barg
  • Resin Format
    Bulk resin

Materials of Construction

  • Base Matrix
    Ceramic Beads

Operating Conditions

  • Operating Pressure
    < 3 barg (44 psi)

Physicochemical Information

  • Ligand
    Methyl
  • Ligand Density
    >250 µeq/mL
  • Reference Protein
    • Bovine serum albumin (BSA)
    • Human polyclonal IgG
  • Typical Dynamic Binding Capacity 10% per mL
    > 50 mg/mL BSA at pH 4.5, 15 mS/cm; 60-100 mg/mL IgG at pH 4 to 5, 4-12 mS/cm

Product Information

  • Brand
    Methyl Ceramic HyperD® F
  • Pack Size
    1
  • Resin Delivery Condition
    1M NaCl with 20% EtOH
  • Resin Type
    Hydrophobic
  • What you receive
    1 bottle resin, instructions

Storage Conditions

  • Storage Conditions
    20% EtOH/1M NaCl