<paragraph>Sartoclear
® Depth Filter Lenticular Modules are stackable depth filters for use in stainless steel housings, which are often used in large scale manufacturing facilities for biologicals.</paragraph><paragraph><bold>Applications:</bold></paragraph><bulletlist><bullet>Mammalian cell culture harvests</bullet><bullet>Microbial lysates</bullet><bullet>Removal of precipitates from sera and plasma</bullet><bullet>Particle and colloid removal from process intermediates</bullet><bullet>Media Filtration</bullet></bulletlist><table style="width: 500px;" border="1" cellspacing="1" cellpadding="1"><thead><tr><th>Grade</th><th>Description</th><th>Application examples
1</th></tr></thead><tbody><tr><td>DL90</td><td>Very coarse primary grade on top of a coarse secondary filter for filtrations with high solid concentrations</td><td>Primary clarification of mammalian cell cultures, insect cell cultures, microbial fermentations, vaccines</td></tr><tr><td>DL75</td><td>Pure cellulose pre-filter combined with a coarse secondary filter</td><td>Primary clarification of mammalian cell cultures, insect cell cultures, microbial fermentations, vaccines</td></tr><tr><td>DL60</td><td>Coarse primary grade with a secondary fine filtration grade for lower to moderate solid concentrations</td><td>Post-perfusion bioreactors, vaccines</td></tr><tr><td>DL20</td><td>Fine filtration grade combined with a standard bioburden reduction grade for the removal of particles</td><td>Post centrifuge mammalian cell cultures, post primary depth filtration, process precipitates</td></tr><tr><td>DL10</td><td>Fine filtration grade followed by an very tight secondary filter for the removal of high concentrations of small particles</td><td>Post centrifuge microbial (e.g. E. coli) lysates, post primary depth filtration step, process precipitates</td></tr><tr><td colspan="3"><small>
1 The listed examples are indicative and need to be confirmed by small scale tests<linebreak/></small></td></tr></tbody></table><paragraph> </paragraph>
