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- Sartocon® Q and Sartocube® Q | TFF Ultrafiltration | Cassettes | Hydrosart® | Q-Screen 30 kDa mAb
Sartocon® Q Cassette | Hydrosart® | 30kDa mAb | 0.63m² | Q-Screen
Sartocon® Q Hydrosart® 30 kDa mAb TFF cassettes for mAb concentration, ultrafiltration and diafiltration. The hydrophilic, non‑protein‑binding cellulose membrane with Q‑Screen channel supports mass transfer even at low feed flow. They have a self‑sealing design, are NaOH cleanable and scalable.
- Price (CNY):
- CNY41,531.10
- Item No.:
- 3021446006Q--SW
- Availability:
- For more information please log in
Sartocon® Q Hydrosart® 30 kDa mAb TFF cassettes for mAb concentration, ultrafiltration and diafiltration. The hydrophilic, non‑protein‑binding cellulose membrane with Q‑Screen channel supports mass transfer even at low feed flow. They have a self‑sealing design, are NaOH cleanable and scalable.
Overview
Specifications
Choose your Sartocon® and Sartocube® | TFF Ultrafiltration | Cassettes
TFF Cassettes for mAb Filtration
Sartocon® Q Hydrosart® 30 kDa mAb features a stabilized cellulose membrane and Q‑Screen channel in a self‑sealing TFF cassette. It supports buffer exchange, volume reduction and target concentration steps for monoclonal antibodies with efficient mass transfer and straightforward scale‑up.
Format and Design
- Self‑sealing cassette format eliminates separate gaskets and simplifies setup.
- Enlarged feed and retentate ports help reduce pressure drop across the device.
- Silicone sealing compound is formulated for low extractables.
- Designed to integrate into TFF filter setups and ultrafiltration cassette platforms.
Membrane and Screen
- Hydrosart® stabilized cellulose membrane with a new 30 kDa molecular‑weight cutoff specifically designed for mAb processing.
- Hydrophilic, non‑protein‑binding surface supports yield and limits nonspecific adsorption.
- Low fouling tendency supports consistent operation.
- Consistent performance maintained even after multiple NaOH cleanings, ensuring reliable repeated use.
- The advanced new screen type, called Q-Screen, enables higher final antibody concentrations.
- High permeate flow enables efficient processing at both medium and high concentrations.
- This medium channel promotes mass transfer even at low feed flow for efficient throughput.
Applications
- Concentration of monoclonal antibody solutions prior to formulation.
- Ultrafiltration and diafiltration for buffer exchange and volume reduction.
- TFF process development, scale‑up, and manufacturing runs.
Advantages at a Glance
- New designed 30 kDa cutoff for consistent separation performance.
- Scalable platform from development to production with reproducible retention at a high level.
- Processing of medium and high viscocities with high flow of permeate.
- Stable flows after NaOH cleaning.
- Broad pH compatibility aligned with common bioprocess requirements.
- Simplified handling and cleaning to support efficient turnaround.
Applications
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IndustryPharma / Biotech
Compliance Information
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Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
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ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Dimensions
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Filtration Area0.63 m²
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Flow Channel GeometryProtein conc. <20% /or viscosity max.3cp
General Specifications
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Cassette FormatSartocon Cassettes
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Filter ClassUltrafilter
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Filter FormatCassettes
Materials of Construction
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Membrane MaterialHydrosart®
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Sealing CompoundSilicone White (High chemical resistance)
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SpacerPolypropylene (PP)
Operating Conditions
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Maximum Inlet Pressure4 bar
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pH StabilitypH 2 – 14
Physicochemical Information
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MWCO30 kDa mAb
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Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Product Information
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BrandSartocon®
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Pack Size1
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TypeQ-Screen (Medium viscosity)