SDR HyperD® for solvent detergent removal in bioprocessing features high capacity for a wide range of detergents and secures high recovery of protein. The resin is composed of silica beads whose pores are filled with a three-dimensional crosslinked hydrophobic polymer. The small pore size, particle size distribution (40 to 100 μm), and hydrophobic nature of the chemical groups make SDR HyperD® resin ideal for detergent removal.
Features and Benefits
- High dynamic binding capacity for many different detergents
- High recovery for proteins
- Ideal tool for both removing solvent and detergent
- Stable in acid, polar organic, and oxidizing solutions
Applications
- Binds detergent molecules typically used in viral inactivation processes [i.e., Tri-n-Butyl Phosphate (TnBP) and Triton X-100]
- Removal of both ionic and zwitter ionic detergents from biological solutions
