Sartoclean® CA Prefiltration Filters
Sartoclean® CA filter elements provide efficient prefiltration for biopharmaceutical liquids, combining particle removal with bioburden reduction. The double-layer cellulose acetate membrane supports high product recovery and economical, stable processing across scales.
Key Features
- Double-Layer Construction: Two cellulose acetate layers increase dirt holding capacity and throughput, reducing changeouts and helping maintain stable flow over longer cycles.
- Low Adsorption Membrane: Cellulose acetate shows very low non-specific binding, which helps maximize protein yield and preservative recovery in sensitive formulations.
- Robust At High Differential Pressure: Mechanical and thermal resistance support operation up to 5 bar differential pressure, sustaining performance in demanding unit operations.
- Scalable Portfolio: Various formats with multiple pore sizes enable precise sizing from development to commercial manufacturing.
- Regulatory Compliance: Manufactured to meet non-pyrogenic and non-fiber releasing requirements and supported by comprehensive documentation for qualification.
Applications
- Plasma fractions
- Vaccines
- Purified protein solutions
- mAb
- Diagnostics
- Purified protein solutions
- Biological fluids
- Solutions containing preservatives
Benefits
- High Product Recovery: Very low non-specific adsorption limits product loss, supporting yield for plasma proteins, vaccine antigens, and purified protein solutions.
- Fewer Filter Changeouts: High throughput and strong particle loading capacity reduce filter replacements, helping shorten process time and labor.
- Stable, Predictable Flow: Consistent clarification improves upstream stability and supports downstream steps by reducing turbidity and particulate burden.
- PFAS: Made without intentionally using PFAS compounds.
- Economic Filtration: Efficient prefiltration lowers overall filter consumption and helps optimize cost per batch while maintaining process performance.
- Easy Scale-Up: Common materials and formats across the range simplify technology transfer from process development to production with predictable results.