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- Sartoflow® Expert SU
Sartoflow® Expert SU
Efficient and Versatile - The TFF System from PD to Pilot
One-skid solution is safe and efficient
A single system streamlines three steps (mixing, filtration, UF/DF) and eliminates product transfer.
Fully scalable single-use solution
Versatile cGMP single-use TFF system provides a seamless transition from 1-20 L scale (i.e. 2 - 100 L starting volume).
Flexible process sequencing
The system has the flexibility to accommodate different sequences of process steps.
Reduced bioburden, ready-to-use system
A gamma-irradiated closed-loop system prevents leaks and eliminates cleaning and validation efforts.
- Item No.:
- SFEXPERTSU
- Availability:
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Efficient and Versatile - The TFF System from PD to Pilot
One-skid solution is safe and efficient
A single system streamlines three steps (mixing, filtration, UF/DF) and eliminates product transfer.
Fully scalable single-use solution
Versatile cGMP single-use TFF system provides a seamless transition from 1-20 L scale (i.e. 2 - 100 L starting volume).
Flexible process sequencing
The system has the flexibility to accommodate different sequences of process steps.
Reduced bioburden, ready-to-use system
A gamma-irradiated closed-loop system prevents leaks and eliminates cleaning and validation efforts.
Overview
Specifications
Choose your Tangential Flow Filtration (TFF) Systems
3-In-1 Single Use Approach
The Sartoflow® Expert SU is a flexible fully automated single-use TFF system for process development and pilot-scale manufacturing in accordance with GMP regulations, running filtration sizes from 0.14 up to 1.4 m² in 1 - 20 L scale.
It streamlines up to three process steps - mixing, sterile-grade filtration and ultrafiltration/diafiltration in a robust fully single-use closed loop, to ensure operator safety, product integrity and process quality.
The Sartoflow® Expert SU features an intuitive visual and software-based guidance to ensure the correct installation of the single-use components. Several peristaltic pumps are available for automated transfer and addition of process fluids.
Transform Your Bioprocessing Efficiency with the Sartoflow® Expert SU System
Features & Benefits of the Sartoflow® Expert SU System
- Automated workflow
- Closed-loop design
- Multi-process capability
- Broad application spectrum
- Single-use design
- Multiple unit operations in one system
- Enhanced process controls
- Batch size adaptability
- Gamma-irradiated flow kits
- Intuitive interface
Consumables for the Sartoflow® Expert SU
The Sartoflow® Expert SU is compatible with the following TFF cassettes:
- Sartocon® Slice Self-Contained ECO
- Sartocube® Self-Contained ECO
The Sartoflow® Expert SU is compatible with the following flow kit:
- Sartoflow® Expert SU Permeate and Retentate Flow Kit (SFE-TUB-PERM-RET)
- Sartoflow® Expert SU Feed Flow Kit (SFE-TUB-FEED)
- Sartoflow® Expert SU Prefiltration Flow Kit (SFE-TUB-PRECIFIL)
- Sartoflow® Expert SU Media Addition Flow Kit (SFE-TUB-MANIFOLD)
- Mycap® Single-Use Cap (MYCAPSSBL0001)
The Sartoflow® Expert SU is compatible with the following bag:
- Recirculation - 20 L 3D mixing bag with sampling port, conductivity probe (FMS310600)
- 2nd Mixing Bag (only for configured system) - 20 L 3D mixing bag with sampling port, pH probe (FMS310569)
Applications
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Application
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
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Concentration
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Microfiltration
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Ultrafiltration
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Desalting
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Buffer Exchange
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Single Use Processing
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Antibody Purification
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Protein Concentration
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DNA Concentration
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mRNA concentration
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Conjugation
- ADC
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
Connections (Physical)
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Connector(s)
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MPC
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AseptiQuik® Connector
- Luer connectors
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MPC
Dimensions
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Dimensions WxDxHBase Unit: 1,430 x 755 x 1,755 mm (nominal) With 2nd bag holder: 1,875 x 755 x 1,755 mm (nominal)
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Membrane Area0.14, 0.28, 0.42, 1.4 m²
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Tube Size (ID – OD)3/8"
Features
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DisplayColored Touchscreen
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Display Size22"
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Sensors
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pH
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Conductivity
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Pressure
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Flow
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Temperature
- UV
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pH
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Temperature ControlRefrigerated and heated
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Temperature SensorpT100
General Specifications
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Cassette Format
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Sartocon® SCU
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Sartocube® SCU
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Sartocon Cassettes
- Sartocube Cassettes
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Sartocon® SCU
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Filter FormatCassettes
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Pump OutputUp to 900 L/h
Materials of Construction
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Materials of ConstructionStainless steel
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Recirculation Vesselsingle-use
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Tubing Material
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Silicone
- TPE
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Silicone
Operating Conditions
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Maximum Operating Pressure4 bar | 58 psi
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Minimum Operating Volume~ 600 mL
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Recommended Operating Temperature10 to 40 C°
Power Requirements
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Power Requirements100 - 120 V, 50/60 Hz, 9A220 - 240 V, 50/60 Hz, 5A
Product Information
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Brand
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Ambr® crossflow
- Sartoflow®
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Ambr® crossflow
Volume
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Bag Volume1-20 L (20 L 3D mixing bag)
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Hold-up Volume~ 400 mL
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Recirculation Vessel Volume1-20 L (20 L 3D mixing bag)
Weight
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Total Weight450 kg