Tangential Flow Filtration (TFF) Systems

TFF Systems - Process Solutions for Ultrafiltration and Diafiltration

Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.

The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.

Key Features

  • Benchtop to production scale from 100 mL to 200 L
  • Working membrane sizes from 10 cm² to 10 m²
  • Single-use and multi-use
  • Highly- to fully automated
  • Compliancy to cGMP available
  • Modular standard systems allow shorter lead times
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Tangential Flow Filtration (TFF) Systems
Tangential Flow Filtration (TFF) Systems

TFF Systems - Process Solutions for Ultrafiltration and Diafiltration

Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.

The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.

Key Features

  • Benchtop to production scale from 100 mL to 200 L
  • Working membrane sizes from 10 cm² to 10 m²
  • Single-use and multi-use
  • Highly- to fully automated
  • Compliancy to cGMP available
  • Modular standard systems allow shorter lead times
Item No.:
M_Sartoflow_TFF_Systems
Availability:

Overview

Specifications

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Products (4)

Tangential Flow Filtration Systems Portfolio

The TFF systems portfolio contains the following products:

  • Ambr® Crossflow (material number varies)
  • Sartoflow® Smart (SFSMART)
  • Sartoflow® Advanced (SFADVANCED)
  • Sartoflow® SP (SFSP-M-SYS)
  • Sartoflow® Expert SU (SFEXPERTSU)

In addition to these systems, Sartorius also offers a wide range of commercial scale products such as the Sartoflow® 1000 SU, Sartoflow® 4500 SU and TFF ETO MU systems, that are customized to your process needs.

Consumables for the TFF Systems

TFF systems are available for the following TFF Hydrosart® and Polyethersulfone (PES) Cassettes:

  • Sartocon® and Sartocube® (MF | UF)
  • Single-use Sartocon® and Sartocube® Self-Contained Units
  • Sartocon® SP | Single pass TFF Cassettes

TFF systems are available for the following Hollow Fiber TFF Modules:

  • Hollow Fiber TFF | Single-Use | Microfiltration
  • Hollow Fiber TFF | Re-Use | Microfiltration
  • Hollow Fiber TFF | Single-Use | Ultrafiltration (from Lab Scale to Process Scale)
  • Hollow Fiber TFF | Re-Use | Ultrafiltration (from Lab Scale to Process Scale)

Disclaimer: Please note that the TFF Cassettes and Hollow Fiber TFF Modules are not included with the TFF systems and must be ordered separately.

Holders for the TFF Systems

The TFF Systems are compatible with the following holders:

  • TFF FIlter Holders
  • Hollow Fiber Flow Stand | Holder

Disclaimer: Please note that the TFF Holders are not included with the TFF systems and must be ordered separately.

Applications

  • Application
    • Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
    • Concentration
    • DNA Concentration
    • Antibody Purification
    • Desalting
    • Buffer Exchange
    • Protein Concentration
    • Single Use Processing

Product Information

  • Brand
    • Ambr® crossflow
    • Sartoflow®