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Sartoflow® SP | Single Pass TFF | System

Single Pass TFF simplifies ultra-and diafiltration by simultaneous concentration and diafiltration in one single pass instead of multiple recirculation.
  • Pump output: Buffer: 194 ml/min (@ 2 bar) | Feed: 75 ml/min (@ 2 bar)
  • Min. Holdup Volume: < 20 ml
  • Max. Inlet Pressure: 3 bar (43.5 psi)
Item No.: 
SFSP-M-SYS
Availability: 
*Custom/bulk order quotes are provided within 72 hours of request.
Sartoflow® SP | Single Pass TFF | System
Sartoflow® SP | Single Pass TFF | System
Single Pass TFF simplifies ultra-and diafiltration by simultaneous concentration and diafiltration in one single pass instead of multiple recirculation.
  • Pump output: Buffer: 194 ml/min (@ 2 bar) | Feed: 75 ml/min (@ 2 bar)
  • Min. Holdup Volume: < 20 ml
  • Max. Inlet Pressure: 3 bar (43.5 psi)
Item No.:
SFSP-M-SYS
Availability:

Overview

Specifications

Single Pass TFF is capable of simultaneous concentration & diafiltration of an inflow process stream yielding a more efficient buffer exchange and the flexibility to tune the outflow rate & process conditions.

Single Pass System

Sartoflow® SP is a unique system that enables improved diafiltration performance in a single pass.

  • Continuous operation to support high g/m² product loading.​​
  • Unique design reduces footprint for the core process and accessories​.
  • Full control over all process parameters with integrated sensors.
  • Automation to enable processes at constant trans-membrane pressure (TMP) & flowrate (feed, diafiltration buffer & retentate)

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Your Gains Compared to Classic TFF

20x Uptime:Downtime

4x Volumetric Productivity

-60% Footprint and Power Consumption

-15% Buffer Usage

+50% Process Efficiency

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The Sartorius Single Pass TFF Offering

Sartoflow® SP TFF system are designed to be used with the Sartocon® SP cassettes, Sartoflow® SP flow path and Sartocon® Slice SC hydraulic filter holder.

  • SFSP-M-SYS Sartoflow® SP System
  • SFSP-M-TUSET Sartoflow® SP Complete Tubing Set
  • 3Q514459M1465902 Sartocon® SP Cassette | 30kDa | 0.2m² | AseptiQuik®
  • 3T514459M1465902 Sartocon® SP Cassette | 30kDa | 0.2m² | Tri-Clamp
  • 3D540SQ01-01 Sartocon® Slice SC hydraulic Holder

Applications

  • Application
    • Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
    • Concentration
    • DNA Concentration
    • Antibody Purification
    • Desalting
    • Buffer Exchange
    • Protein Concentration
    • Single Use Processing