Sartobind® mAb pack
Choose your Sartobind® Rapid A
Sartobind® Rapid A is a protein A membrane chromatography solution designed to increase the efficiency of antibody purification processes. This platform is well-suited for process intensification, reducing process times due to higher operational flow rates, while maintaining high binding capacities and minimizing back pressure. Altogether, Sartobind® Rapid A has the potential to substantially reduce the cost associated with the mAb capture step, particularly in process development and production of material for early clinical phases.
Available formats:
- 96 Well Plates
- Capsules (1.2 mL, 10 mL, 75 mL and 200 mL)
- Cassette (0.8 L)
Complementary products:
- Rapid A Ligand
- Manifold Pilot Holder
Features and Benefits:
- Time Savings – faster cycling times with membranes mean less time is required for process development and validation. Moreover, column handling operations are no longer necessary.
- Cost reduction – especially for manufacturing of clinical phase material or smaller commercial scale
- Risk mitigation – because membranes are less sensitive to air presence or bed instability issues the risk of production stop is less significant
- Compact footprint and flexibility- smaller bed volumes can purify the same amounts of target molecules in the same amount of time. Furthermore, there is no need for ancillary equipment related to packing and maintenance.
- Scalability
Applications:
- Monoclonal antibody (mAb) purification
- Fc-region containing fusion proteins
- Bi-specifics, multi-specific antibodies
Application Notes
Applications
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ApplicationCapture
Connections (Physical)
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Connector(s)Female Luer lock
Dimensions
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Bed Height4 mm
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Dimensions37 x 31 mm
Materials of Construction
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Housing MaterialPolypropylene (PP)
Operating Conditions
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Maximum Operating Pressure0.4 MPa
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Maximum Venting Pressure0.5 bar, 0.05 MPa, 7 psi
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Recommended Flow Rate3-5 MV/min (load, elution), 5-10 MV/min ( equilibration, wash)
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pH StabilitypH 2 – 14 (short term), pH 3 – 13 (long term)
Physicochemical Information
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Bed Volume1.2 mL, 1 mL, 3 mL
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Chemical CompatibilityStable in common chromatography buffers, unstable to peroxide and other oxidizing or reactive reagents
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LigandProtein A
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Reference ProteinHuman polyclonal IgG
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Typical Dynamic Binding Capacity 10% per mL≥ 30 mg/mL
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Void Volume3.5 mL (4 mm), 4 mL (8 mm)
Product Information
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BrandSartobind® Rapid A
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Membrane Adsorber FormatCapsules
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Membrane TypeAffinity
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Pack Size5
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What you receive
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5 capsules (each Rapid A, S, Q, STIC PA, Phenyl)
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1 operating instruction
- 1 certificate
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5 capsules (each Rapid A, S, Q, STIC PA, Phenyl)