Sartoguard GF | Sartoscale 47 | 0.1µm | 3pc.

Sartoguard GF filter elements are polyethersulfone membrane based prefilters. The membrane double layer is protected by a layer of glass fiber fleece material. They combine the defined retention performance of membrane filters with the high total throughput capacity of depth filter material. Therefore, Sartoguard GF prefilters offering optimal protection of sterile filters and validated bioburden reduction.

The asymmetric polyethersulfone (PES) membranes used in Sartoguard GF filters achieve an LRV of 6 per cm². This significantly reduces the bioburden in the downstream process and protects subsequent purification steps.

Additionally Sartoguard GF filters are ideally suited for the effective retention of colloids and lipids, which quickly block more expensive mycoplasma filters or membrane filters

Main Applications

Sartoguard GF filter elements are typically used for prefiltration of:

• Cell Culture Media
• Buffers
• Serum
• Ophthalmics
• Large Volume Parenterals
• Colloid and lipid containing liquids

Benefits

• More economical process flow
• Downsizing of filtration systems
• Significantly higher total throughput performance
• LRV of 6 per cm2 filtration area for Brevundimonas Diminuta (0.1 µm version) and for Serratia Marcescens (0.2 µm version)

Membrane

The heterogeneous double layer PES membranes provide secure and reliableretention needed for critical applications.

The glassfiber fleece provides high particle loadingcapacity and effective retention of large and small particlesas well as excellent turbidity reduction.

Cost savings:

The use of disposable filter elements eliminates the need to invest in stainless steel filter housings. Additional costs for housing cleaning and cleaning validation are eliminated.

Flexibility

Sartoguard GF filters are available in a wide range of filtration areas from 4.5 cm² up to 1.8 m² and with a variety of commonly used connections to ensure easy integration into your process regardless of batch size.

Scale Up:

Consistent and predictable scale-up and scale-down procedures can be safely performed because all Sartoguard GF filter elements are manufactured with the same membrane type, support fleeces and construction materials.

Sterilization

Sartoguard GF filters have been developed for sterilization using autoclaving at max. 134°C | 2bar.

Quality:

Every single element is tested for integrity to meet the highest quality requirements.

Documentation:

Sartoguard GF filters have been designed, developed and produced in accordance with the ISO 9001 certified quality management system. A validation manual is available in accordance with regulatory requirements.