Sartoguard GF

The asymmetric polyethersulfone (PES) membranes used in Sartoguard GF filters achieve an LRV of 6 per cm². This significantly reduces the bioburden in the downstream process and protects subsequent purification steps.

Additionally Sartoguard GF filters are ideally suited for the effective retention of colloids and lipids, which quickly block more expensive mycoplasma filters or membrane filters

Main Applications

Sartoguard GF filter elements are typically used for prefiltration of:

• Cell Culture Media
• Buffers
• Serum
• Ophthalmics
• Large Volume Parenterals
• Colloid and lipid containing liquids

Benefits

• More economical process flow
• Downsizing of filtration systems
• Significantly higher total throughput performance
• LRV of 6 per cm2 filtration area for Brevundimonas Diminuta (0.1 µm version) and for Serratia Marcescens (0.2 µm version)

Membrane

The heterogeneous double layer PES membranes provide secure and reliableretention needed for critical applications.

The glassfiber fleece provides high particle loadingcapacity and effective retention of large and small particlesas well as excellent turbidity reduction.

Cost savings

The use of disposable filter elements eliminates the need to invest in stainless steel filter housings. Additional costs for housing cleaning and cleaning validation are eliminated.

Flexibility

Sartoguard GF filters are available in a wide range of filtration areas from 4.5 cm² up to 1.8 m² and with a variety of commonly used connections to ensure easy integration into your process regardless of batch size.

Scalability

Consistent and predictable scale-up and scale-down procedures are ensured with Sartoguard GF filter elements, as they are all crafted using the same membrane type, support fleeces, and construction materials, providing reliability across applications.

Quality

Each element undergoes integrity testing to meet stringent quality standards, ensuring reliable performance in its applications.

Documentation:

Sartoguard GF filters have been designed, developed and produced in accordance with the ISO 9001 certified quality management system. A validation manual is available in accordance with regulatory requirements.

Sterilizing grade and bioburden reduction offering

Sterilizing grade filters

• Sartopore®: Polyethersulfone membrane
• Sartobran® P: Cellulose acetate membrane
• Sartolon: Polyamide membrane

Bioburden reduction filters

• Sartoguard: Polyethersulfone membrane
• Sartoclean®: Cellulose acetate membrane