Virosart® CPV is optimized for robust and high-capacity virus filtration of monoclonal antibodies, ensuring efficient viral clearance. Available in various device formats, including cartridges and capsules, it achieves significant logarithmic reduction values, maintaining process integrity in biopharmaceutical manufacturing.

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Virosart® CPV
Virosart® CPV

Virosart® CPV is optimized for robust and high-capacity virus filtration of monoclonal antibodies, ensuring efficient viral clearance. Available in various device formats, including cartridges and capsules, it achieves significant logarithmic reduction values, maintaining process integrity in biopharmaceutical manufacturing.

Item No.:
M_Virosart_CPV

Overview

Specifications

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The Virosart® CPV filters are used in the biopharmaceutical industry to ensure the protection and purity of products by removing viruses from process fluids. Virosart® CPV product family is designed specifically to meet the diverse needs of monoclonal antibody applications, from laboratory research to large-scale manufacturing. They are designed to provide robust performance and high virus retention while maintaining product yield and process efficiency.

Key Features:

  • Membrane Technology: Asymmetric Polyethersulfone (PES) Membrane: The PES membrane is engineered to process monoclonal antibodies and recombinant proteins.
  • High Virus Retention: Achieves significant logarithmic reduction values for both enveloped and non-enveloped viruses, ensuring effective virus clearance across various operating conditions.
  • Efficient Process Integration: Designed for seamless integration into existing single-use and stainless steel facilities, minimizing downtime and optimizing workflow.
  • Regulatory Compliance: Manufactured under ISO 9001 certified Quality Management System and non-pyrogenic as per USP Bacterial Endotoxins standards.
  • Versatile Device Formats: Available as cartridges and self-contained capsules.
  • Integrity Testing: Reliable integrity testing using Sartocheck® technology. Furthermore, each unit is integrity tested (except non-IT tested version of Minisart®, see specifications) and complies with industry standards, ensuring reliability and performance.
  • Operating Parameters:
    Filtration pressure: Max. 5.0 bar (72.5 psi) at 20°C; 0.2 bar (2.9 psi) at 121°C.
    Reversed filtration pressure: Max. 0.2 bar (2.9 psi) at 20°C.

Ordering Information:

  • Cartridge Options: Multiple sizes; autoclavable and steamable.
  • Maxicaps®: Self-contained, various sizes of different filtration areas.
  • Midicaps® & Capsules: Self-contained, sanitary connectors for easy installation as well as hose barb for capsules.

Applications

  • Application
    • mAB Production
    • Recombinant Protein Production

Materials of Construction

  • Filter Material
    Polyethersulfone (PES)

Physicochemical Information

  • Pore Size
    20 nm (nominal)

Product Information

  • Brand
    Virosart® CPV