Sartocon® Slice 50 | Hydrosart® | 300kDa | 50cm² | ECO

The Sartocon® Slice 50 is a ready to use 50 cm²fully disposable crossflow module that is ideally suited for membrane screening and process development, available in a wide variety of MWCO’s and polymers. The Sartocon® Slice 50 can easily be used with the Sartoflow® Smart system as well as many other laboratory scale crossflow systems. Sartocon® Slice 50 is available with both Hydrosart® and Polyethersulfone membranes. It can easily be used with the Sartoflow® Smart system.

Applications

Typical 300 kDa TFF Applications are Ultrafiltration and Diafiltration of

• Large Viruses such as MVA for Smallpox and Monkeypox vaccine
• Virus like particles
• pDNA and mRNA
• Blood and Plasma
• Protein solutions
• Polysaccharide solutions
• Large mAb constructs
• Removal of Contaminants

Hydrosart® Membrane

Hydrosart® high performance membrane is a stabilized cellulose-based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane depyrogenation can be accomplished by using NaOH even at elevated temperatures. These features make Hydrosart® an ideal membrane for biological applications.

Flow Channel Geometry

Sartocon® Slice 50 is available in two flow channel geometry versions. E-Screen filters are dominantly used for protein concentrations up to above 20% as well as viscosity conditions greater than 3 cp. ECO-Screen devices mainly used for water based protein solutions of below 20% protein concentration as well as lower than 3 cp viscosity.

Advantages

Sartocon® Slice 50 is available in all membrane materials and cut offs and enables flexibility in membrane screening.The Self contained design features ease of use. No further compression holder is needed. The low membrane adsorption ensures minimal product loss as well as high flux and product yieldA Data Matrix code ensures fast access to the order code and shelf life data.Luerlock Female ports ensure a Quick connection to the Sartoflow® Smart systemThe low hold up volume design allows a high concentration factor.

Available Cut-Offs

Hydrosart®: 2kDa, 5 | 10 | 30 | 100 | 300 kDa

Polyethersulfone: 1 | 5 | 8 | 10 | 30 | 50 | 100 | 300 kDa

Regulatory Compliance

All product contact materials have passed the current USP Biological Test and Cytotoxicity Test. All materials are BSE and TSE free. The filtrate meets or exceeds the currently valid USP and EP for sterile Water for Injection, with respect to extractable substances, oxidizable substances and Bacteria Endotoxins.