Sartoflow® Smart

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Sartoflow® Smart Sartoflow® Smart Sartoflow® Smart Sartoflow® Smart
 

Smart & Easy - The TFF System from PD to GMP

Excellent flexibility


50 cm² - 0.14 m² membrane size | 1 L PSU vessel or 150 mL - 1 L single-use Flexboy® bags for recirculation

Intuitive and comfortable


User-friendly through high level of automation with automatic retentate valve and external feeding pump

Highest product yields


Low recirculation volume at 20mL and low shear 4-piston membrane pump

Item No.: 
SFSMART
Availability: 
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

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Application & Configuration

The Sartoflow® Smart is suitable for use in laboratory environments for process development and clinical trials as well as for cGMP environments.

It can be configured to accept either Sartocon® Slice 200 or Sartocon® Slice ECO UF cassettes. An optional holding device for 50 cm2 TFF modules e.g. Sartocon® Slice 50 is available.

The recirculation tank utilizes a load cell for level control and can be replaced by a recirculation bag stand with Flexboy® bags.

Pivotal for Process Scalability

The Sartoflow® Smart TFF system is the ideal tool for developers establishing and refining process parameters in scale-up and scale-down studies. Achieve stable values for retentate pressure or transmembrane pressure (TMP) by applying the automated retentate valve and diafiltration pump.

This enables

  • Low minimum sample volume

  • Low minimum recirculation volume

  • Easy data access

  • High level of automation for data continuity and reproducibility

  • Full transferability of process data to large-scale systems

Applications

  • Application
    Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins

Dimensions

  • Dimensions WxDxH
    602 × 440 × 610 mm
  • Membrane Area
    50 cm² - 0.14 m²

General Specifications

  • Cassette Format
    • Slice Cassettes
    • Slice 50 Cassettes
    • Standard Cassettes
  • Filter Format
    Cassettes
  • Pump Output
    1 – 100 L/h @ 3 bar (43.5 psi)

Materials of Construction

  • Recirculation Vessel
    Polysulfone (PSU)

Operating Conditions

  • Maximum Operating Pressure
    3 bar (44 psi)
  • Minimum Operating Volume
    < 20 mL

Power Requirements

  • Power Requirements
    230 VAC | 50 Hz 2 Amp; 120 VAC | 60 Hz 3 Amp

Volume

  • Hold-up Volume
    < 20 mL
  • Recirculation Vessel Volume
    1 L (MU)
  • Volume
    Bag: 1.5 - 3 L (SU)

Weight

  • Total Weight
    ~ 35 kg