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- Sartoflow® Advanced
Sartoflow® Advanced
Full Flexibility Meets Outstanding TFF Performance
Flexible solution
0.1 - 2.1 m² membrane sizes | 10 L stainless steel vessel or 5, 10, 20 L single-use bags for recirculation
High product yields
4-piston membrane pump for low shear
Highly automated
Two pumps for feed and buffer addition, as well as full TMP control
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Full Flexibility Meets Outstanding TFF Performance
Flexible solution
0.1 - 2.1 m² membrane sizes | 10 L stainless steel vessel or 5, 10, 20 L single-use bags for recirculation
High product yields
4-piston membrane pump for low shear
Highly automated
Two pumps for feed and buffer addition, as well as full TMP control
Overview
Specifications
Choose your Tangential Flow Filtration (TFF) Systems
Application & Configuration
The Sartoflow® Advanced is a modular crossflow system for ultrafiltration, microfiltration and diafiltration applications in many biopharmaceutical processes, such as the purification of vaccines, monoclonal antibodies and recombinant proteins. The Sartoflow® Advanced can also be used under demanding laboratory and production conditions.
TFF Cassettes for the Sartoflow® Advanced
Sartocon® Slice with 0.1 m² membrane area
- Hydrosart® UF membrane - MWCO 2, 5, 10, 30, 100 kD
- PESU UF membrane - MWCO 1, 5, 8, 10, 30, 50, 100, 300 kD and Albumin
- Hydrosart® MF membrane - MWCO 0.2 and 0.45 μm
- PESU MF membrane - MWCO 0.1 μm
Sartocon® Slice with 0.14 - 0.7 m² membrane area
- Hydrosart® membrane - MWCO 10, 30, 100 kD
Applications
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Application
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
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Ultrafiltration
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Diafiltration
- Microfiltration
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
Connections (Physical)
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Connector(s)0.5" Tri-clamp
Dimensions
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Dimensions WxDxH1,100 × 800 × 680 mm
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Membrane Area0.1 - 0.5 m² (optionally 0.7 - 2.1 m²)
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Tube Size (ID – OD)1/2"
Features
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DisplayYes
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Display Size12" (800 x 600 pixel)
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Sensors
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Pressure
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Flow
- Temperature
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Pressure
General Specifications
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Cassette Format
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Sartocon Cassettes
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Slice Cassettes
- Standard Cassettes
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Sartocon Cassettes
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Filter FormatCassettes
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Pump Output700 L/h @ 4 bar (60 psi)
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Surface Roughness of Wetted PartsRa <= 0.6 µm
Materials of Construction
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Recirculation VesselStainless steel 316 L
Operating Conditions
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Maximum Operating Pressure4 bar (60 psi)
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Minimum Operating Volume~200 mL
Power Requirements
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Power Requirements230 VAC | 50 Hz 2.5 Amp;120 VAC | 60 Hz 4 Amp
Product Information
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BrandSartoflow®
Volume
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Bag Volume5, 10, 20 L (SU)
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Recirculation Vessel Volume10 L (MU)
Weight
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Total Weight~ 120 kg (~265 lbs.)