Sartoguard PES | Gamma Midicaps® | 0.2µm | Size 7 | 4pc
- Effective Filtration Area: 0.065 m² | 0.7 ft²
- Pore Size: 1.2 µm prefilter | 0.2 µm final filter
- Connectors: Inlet: Sanitary 1 ½“| Outlet: Hose Barb ½“ single stepped
- Sterilization: Gamma-irradiatable
- Membrane Material: Polyethersulfone
- Pack Size: 4 pieces
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Connector explanation:
O = Hose Barb ½“ | S = Sanitary 1 ½“ | H = Hose Barb ¼“ | F = Sanitary ¾“
Size explanation:
Size 7 = 0.065 m² | Size 8 = 0.13 m² | Size 9 = 0.26 m² | Size 0 = 0.52 m²
- Item No.:
- 5475307F7G-SO--A
- Pieces
- 4
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Sartoguard
The asymmetric polyether sulfone (PES) membranes used in Sartoguard PES filters achieve an LRV of 6 per cm². This significantly reduces the bioburden in the downstream process and protects subsequent purification steps. When used upstream of sterilization grade filters, Sartoguard PES increases overall throughput and reduces the number of filters required and process costs.
Main Applications
- Bioburden reduction in protein- and virus-based therapies as well as in processes producing pDNA/mRNA based therapies
- Protection of purification equipment and sterilizing-grade filters
Benefits
- More economical process flow
- Downsizing of filtration systems
- Significantly higher total throughput performance
- LRV of 6 per cm2 filtration area for Brevundimonas Diminuta (0.1 µm version) and for Serratia Marcescens (0.2 µm version)
Membrane
Sartoguard PES uses a heterogeneous double membrane made of polyethersulfone
Compatibility
Sartoguard PES Gamma filters have been developed for sterilization using gamma irradiation < in 50 kGy irradiation doses. The SartoguardPES polyethersulfone membrane has a high chemical compatibility between pH 1 to 14, making Sartoguard PES Gamma filters ideally suited for the filtration of high and low pH solutions in pharmaceutical | Biotech Industry
Cost savings:
The use of disposable filter elements eliminates the need to invest in stainless steel filter housings. Additional costs for housing cleaning and cleaning validation are eliminated.
Flexibility
Sartoguard PES filters are available in a wide range of filtration areas from 4.5 cm² up to 1.8 m² and with a variety of commonly used connections to ensure easy integration into your process regardless of batch size.
Scale Up:
Consistent and predictable scale-up and scale-down procedures can be safely performed because all Sartoguard PES filter elements are manufactured with the same membrane type, support fleeces and construction materials.
Quality:
Every single element is tested for integrity to meet the highest quality requirements.
Documentation:
Sartoguard PES filters have been designed, developed and produced in accordance with the ISO 9001 certified quality management system. A validation manual is available in accordance with regulatory requirements.
Applications
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Application
-
mAB Production
- Protection of Final Filters
-
mAB Production
-
IndustryPharma / Biotech
-
Modality
-
Media Filtration
-
Harvest | Cell Removal
- Filtration after Virus Inactivation
-
Media Filtration
Compliance Information
-
Bacterial Endotoxins< 0.25 EU/mL as determined by the LAL test
-
Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
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ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Connections (Physical)
-
Connector Inlet1.5" Tri-clamp 50 mm
-
Connector Outlet1/2" Single Stepped Hose Barb
Dimensions
-
Filter Sizesize 7 (0.065 m² / 0.7 ft²)
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Outer Diameter108.5 mm (77 mm without Connection / Valves)
General Specifications
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Capsule/Cartridge FormatMidicaps®
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Filter FormatCapsules
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Maximum Diffusion3 mL/min at 1.2 bar | 17.5 psi
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Minimum Required Bubble Point1.8 bar | 26 psi
Materials of Construction
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Housing MaterialPolypropylene (PP)
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Material o-ring | sealSilicone (SI)
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Membrane MaterialPolyethersulfone (PES)
-
Support FleecePolyester (PET)
Operating Conditions
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Maximum Differential Pressure5 bar
Physicochemical Information
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Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
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Pore Size Final-filter0.2 µm
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Pore Size Pre-filter1.2 µm
Product Information
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BrandSartoguard PES
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Pack Size4
Sterility/Purity
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Delivery ConditionNon sterile - Gamma irradiatable
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Sterilization MethodGamma Irradiatable
Usage Protocols
-
Sterilization ProceduresGamma Irradiation: with 50 kGy
The Sartopure® filter family is optimized for the clarification and retention by utilizing multiple layers of progressively finer pleated polypropylene or adsorptive glass fleece material. The turbidity reduction results in optimal protection of all downstream material like chromatographic columns or membrane filters.