Sartoguard® PES prefilters combine high throughput with excellent clarification for cell culture media and clarified harvests. Nominal 0.1 and 0.2 µm options with LRV 6 per cm² support effective bioburden control and protect final sterilizing filters.

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Sartoguard PES
Sartoguard PES

Sartoguard® PES prefilters combine high throughput with excellent clarification for cell culture media and clarified harvests. Nominal 0.1 and 0.2 µm options with LRV 6 per cm² support effective bioburden control and protect final sterilizing filters.

Item No.:
M_Sartoguard_PES

Overview

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Sartoguard PES Prefilters

Sartoguard PES filters support bioburden reduction and membrane prefiltration for cell culture media and clarified harvests. High throughput and strong clarification help shorten cycles while protecting final sterilizing filters and downstream equipment.

Key Features

  • Dual-Layer PES Membrane: Their two membrane layer design pairs clarification with bioburden retention, supporting stable flow and efficient prefiltration.
  • High Throughput and Clarification: Sartoguard PES delivers excellent clarification of process fluids, helping reduce filter count and time per batch.
  • Integrity Testable: On-site diffusion and bubble point testing support reliable qualification and routine release in development and production.
  • Proven Bacteria Retention: Typical LRV 6 per cm² for Serratia marcescens (0.2 µm nominal) provides robust bioburden reduction for process fluids.
  • Scalable Portfolio: Membrane areas from 4.5 cm² to 2.4 m² per element enable linear scale-up and economic sizing from PD to process scale.

Applications

  • Cell Culture Media
  • Downstream Intermediates
  • Clarified cell culture harvest
  • Buffers
  • Aseptically filled Small Volume Parenteral
  • Protection of final filters (before and after UF | DF and chromatography steps)

Benefits

  • Efficient Bioburden Control: Retention performance and clarification help reduce microbial load and particulates, supporting consistent upstream and intermediate steps.
  • Protection of Final Filters: Prefiltration reduces fouling of sterilizing-grade membranes, extending service life and helping to stabilize flow.
  • Shorter Filtration Cycles: High throughput and economic sizing options support reduced processing time and streamlined operations.
  • PFAS: Made without intentionally using PFAS compounds.
  • Reliable Process Verification: Integrity testing by diffusion and bubble point supports reproducible qualification and confident release decisions.
  • Seamless Scale-Up: Common materials and a wide area range simplify transitions from development to commercial scale and help standardize validation.

Applications

  • Application
    • mAB Production
    • Protection of Final Filters
  • Modality
    • Media Filtration
    • Harvest | Cell Removal
    • Filtration after Virus Inactivation

Materials of Construction

  • Membrane Material
    Polyethersulfone (PES)

Physicochemical Information

  • Pore Size Final-filter
    0.1 µm or 0.2 µm
  • Pore Size Pre-filter
    0.8 µm or 1.2 µm

Product Information

  • Brand
    Sartoguard PES